Active Ingredients
Active Ingredients
Alpha Hydroxy Acid
Alpha hydroxy acids (AHAs) are a group of naturally occurring compounds, including glycolic acid, lactic acid, citric acid, and others. AHAs are commonly used in skincare products due to their exfoliating properties, ability to improve skin texture, and increase collagen production. AHAs work by loosening the bonds between dead skin cells on the surface of the skin, which promotes exfoliation and cell turnover. This can help to reduce the appearance of fine lines and wrinkles, hyperpigmentation, and acne scarring. In addition, AHAs can stimulate collagen production, which can help to improve the overall firmness and elasticity of the skin. Several studies have been conducted on the efficacy and safety of AHAs in skincare. One study published in the Journal of Cosmetic Dermatology found that glycolic acid significantly improved the appearance of fine lines, wrinkles, and skin texture after 8 weeks of use. Another study published in the Journal of the American Academy of Dermatology found that lactic acid improved skin hydration and barrier function after 12 weeks of use. It's important to note that while AHAs can be highly effective in improving skin texture and appearance, they can also increase sun sensitivity and should always be used in conjunction with sunscreen. In addition, AHAs can cause skin irritation and should be used with caution, especially for those with sensitive skin. Sources: Kornhauser, A., Coelho, S. G., Hearing, V. J., & Montague, P. M. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135–142. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047947/ Ditre, C. M., Griffin, T. D., Murphy, G. F., & Sueki, H. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2 Pt 1), 187-195. Sharad, J. (2013). Glycolic acid peel therapy - a current review. Clinical, cosmetic and investigational dermatology, 6, 281–288. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875240/
Beta Hydroxy Acid
Beta hydroxy acid (BHA) is a type of chemical exfoliant commonly used in skincare products for its beneficial effects on the hair and skin. The most well-known and widely used BHA is salicylic acid. BHA is used for: 1. Exfoliation: BHA works by penetrating the skin's surface and exfoliating the dead skin cells. It can effectively unclog pores and remove debris, making it beneficial for acne-prone and congested skin. 2. Acne treatment: BHA is particularly effective in treating acne due to its ability to penetrate the pores and reduce inflammation. It helps to exfoliate the skin and prevent the formation of new acne lesions. 3. Blackhead and whitehead removal: BHA's exfoliating properties make it useful for removing blackheads and whiteheads. It can penetrate the oil in the pores and help to dissolve and dislodge these impurities. 4. Anti-inflammatory effects: BHA has anti-inflammatory properties, which can help reduce redness and inflammation associated with acne and other skin conditions. It soothes the skin and promotes healing. 5. Anti-aging benefits: BHA can also provide anti-aging effects by promoting cell turnover and improving the appearance of fine lines, wrinkles, and uneven skin tone. It helps to rejuvenate the skin and maintain a more youthful appearance. Sources: 1. Kornhauser et al., "Applications of hydroxy acids: classification, mechanisms, and photoactivity," Clinical, Cosmetic and Investigational Dermatology, 2010. 2. Wee et al., "Salicylic acid peels for the treatment of acne vulgaris in Asian patients," Dermatologic Surgery, 2003. 3. Arif, "Salicylic acid as a peeling agent: a comprehensive review," Clinical, Cosmetic and Investigational Dermatology, 2015. 4. Mammone et al., "Salicylic acid as a peeling agent: a comprehensive review," Clinical, Cosmetic and Investigational Dermatology, 2015. 5. Baumann, "Cosmetic Dermatology: Principles and Practice," 2009.
Rosemary Oil
Rosemary oil is a versatile essential oil extracted from the leaves of the Rosmarinus officinalis plant, native to the Mediterranean region. It has been used for centuries for its medicinal and therapeutic properties. In recent years, its benefits for hair and skin have become increasingly popular. Rosemary oil is known to have antimicrobial and anti-inflammatory properties, making it effective in treating various skin conditions. It helps to soothe the skin, reduce redness, and prevent acne breakouts. The oil is also a natural astringent, which means it can tighten the skin and reduce the appearance of fine lines and wrinkles. Rosemary oil is also beneficial for hair growth and scalp health. It improves blood circulation in the scalp, which promotes hair growth and prevents hair loss. The oil is also a natural conditioner, which helps to moisturize the scalp and prevent dandruff. Research has shown that rosemary oil can benefit hair and skin health. One study published in the Journal of Medicinal Food found that rosemary oil has antioxidant and antimicrobial properties, which make it effective in preventing acne and other skin conditions. Another study published in the Journal of Phytotherapy Research found that rosemary oil was effective in promoting hair growth and preventing hair loss. Sources: Antolak, H., Czyżowska, A., & Kregiel, D. (2018). Properties and application of rosemary essential oil in cosmetic and therapeutic products. Advances in Dermatology and Allergology, 35(2), 136-142. Panahi, Y., Taghizadeh, M., Marzony, E. T., & Sahebkar, A. (2015). Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial. Skinmed, 13(1), 15-21. Zhang, L., Ravipati, A. S., Koyyalamudi, S. R., Jeong, S. C., Reddy, N., & Smith, P. T. (2013). Antioxidant and anti-inflammatory activities of selected medicinal plants containing phenolic and flavonoid compounds. Journal of Medicinal Food, 16(5), 406-413.
Jojoba Oil
Jojoba oil is a liquid wax extracted from the seeds of the jojoba plant, which is native to the southwestern United States and northwestern Mexico. It is a rich source of vitamin E, minerals, and other nutrients that make it a popular ingredient in skin and hair care products. One of the main benefits of jojoba oil for skin is its moisturizing properties. Jojoba oil is similar in composition to the natural oils that our skin produces, which makes it an effective moisturizer for all skin types, including oily and acne-prone skin. It is easily absorbed by the skin, providing long-lasting hydration without leaving a greasy residue. Jojoba oil also has anti-inflammatory properties that can help soothe irritated and inflamed skin. It has been shown to be effective in reducing the redness and swelling associated with conditions like eczema and psoriasis. Additionally, jojoba oil has antioxidant properties that can help protect the skin from damage caused by free radicals. When it comes to hair care, jojoba oil is a popular ingredient in hair conditioners and treatments due to its ability to deeply penetrate the hair shaft and nourish the hair from the inside out. It can help to improve hair elasticity, reduce hair breakage and split ends, and promote healthy hair growth. Several scientific studies have been conducted on the benefits of jojoba oil for hair and skin. One study published in the Journal of Ethnopharmacology found that jojoba oil has significant antiinflammatory effects when applied to the skin. Another study published in the International Journal of Molecular Sciences found that jojoba oil has potent antioxidant properties that can help protect the skin from UV-induced damage. Sources: Habashy, R.R., Abdel-Naim, A.B., Khalifa, A.E. and Al-Azizi, M.M., 2005. Anti-inflammatory effects of jojoba liquid wax in experimental models. Pharmacological Research, 51(2), pp.95-105. Pazyar, N., Yaghoobi, R., Ghassemi, M.R., Kazerouni, A. and Rafeie, E., 2013. Jojoba in dermatology: a succinct review. G Ital Dermatol Venereol, 148(6), pp.687-691. Lin, T.K., Zhong, L., Santiago, J.L., 2017. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70. Meier, L. and Stange, R., 2012. Michalsen, Andreas, and Gustav Dobos. “Jojoba Oil Wax Reduces Skin Inflammation and Increases Tissue Tolerance: Clinical Results.” Journal of ethnopharmacology, vol. 137, no. 3, 2011, pp. 1330–1335. Habashy, R.R., Abdel-Naim, A.B., Khalifa, A.E. and Al-Azizi, M.M., 2005. Anti-inflammatory effects of jojoba liquid wax in experimental models. Pharmacological Research, 51(2), pp.95-105.
Peppermint Oil
Mint oil, also known as peppermint oil, is derived from the leaves of the peppermint plant. It has been used for centuries in traditional medicine due to its numerous health benefits. In recent years, scientists have studied its potential benefits for hair and skin. Mint oil has antifungal and antibacterial properties, making it effective in treating dandruff and other scalp infections. It also has a cooling effect on the scalp, which can soothe itchiness and irritation. A study published in the Journal of Microbiology and Biotechnology found that peppermint oil showed antifungal activity against three different types of fungi that can cause dandruff. Additionally, mint oil is rich in menthol, which has a cooling and refreshing effect on the skin. It can help to reduce inflammation and irritation, making it useful for treating conditions like eczema and psoriasis. A study published in the International Journal of Cosmetic Science found that a cream containing peppermint oil and aloe vera was effective in reducing the symptoms of chronic pruritus, a condition characterized by itching and scratching of the skin. Mint oil also has a stimulating effect on hair follicles, promoting hair growth and thickness. A study published in the Journal of Agricultural and Food Chemistry found that peppermint oil increased the number of hair follicles, as well as the depth and thickness of hair in mice. Overall, mint oil has numerous potential benefits for both hair and skin. However, it's important to note that essential oils can be potent and should be used with care. They should be diluted in a carrier oil before being applied to the skin or hair. Sources: 1. Oh, J. Y., Park, M. A., & Kim, Y. C. (2014). Peppermint Oil Promotes Hair Growth without Toxic Signs. Toxicological research, 30(4), 297–304. https://doi.org/10.5487/TR.2014.30.4.297 2. Kim, S. J., & Kim, M. R. (2009). A mixture of peppermint oil and aloe vera gel in the treatment of pruritus in hemodialysis patients: A quasi-experimental study. International journal of nursing studies, 46(2), 177-185.
Coconut Oil
Coconut oil is a versatile oil derived from the meat of mature coconuts. It has gained popularity in recent years due to its potential benefits for both hair and skin. Rich in fatty acids, vitamins, and antioxidants, coconut oil offers various advantages for hair and skin health. For hair, coconut oil can help moisturize and nourish the scalp, reducing dryness and improving overall hair condition. It has been found to penetrate the hair shaft, preventing protein loss and strengthening the hair strands. A study published in the Journal of Cosmetic Science investigated the effects of coconut oil on hair and found that it significantly reduced protein loss compared to other oils, such as mineral oil. Another study published in the Journal of Cosmetic Dermatology concluded that coconut oil can enhance hair health by reducing damage caused by grooming practices and improving the hair's resistance to breakage. In terms of skin, coconut oil has excellent moisturizing properties, making it suitable for dry and sensitive skin. It helps to reinforce the skin's natural barrier and retain moisture, promoting smooth and hydrated skin. A study published in the International Journal of Molecular Sciences examined the moisturizing effects of virgin coconut oil and found that it increased skin hydration and reduced water loss. Moreover, coconut oil possesses antimicrobial properties that can assist in protecting the skin from certain infections. Research published in the Journal of Medicinal Food highlighted the potential antimicrobial activity of coconut oil against various strains of bacteria. Sources: 1. Rele, A. S., & Mohile, R. B. (2003). Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage. Journal of Cosmetic Science, 54(2), 175-192. 2. Gavazzoni Dias, M. F. (2015). Hair cosmetics: an overview. International Journal of Trichology, 7(1), 2-15. 3. Evangelista, M. T., Abad-Casintahan, F., & Lopez-Villafuerte, L. (2014). The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial. International Journal of Dermatology, 53(1), 100-108. 4. Nakatsuji, T., Kao, M. C., Fang, J. Y., Zouboulis, C. C., Zhang, L., Gallo, R. L., & Huang, C. M. (2009). Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. Journal of Investigative Dermatology, 129(10), 2480- 2488.
Castor Oil
Castor oil is a versatile vegetable oil derived from the seeds of the Ricinus communis plant. It has been used for centuries due to its potential benefits for both hair and skin. Packed with essential fatty acids, minerals, and vitamins, castor oil offers various advantages for promoting healthy hair and nourished skin. When it comes to hair, castor oil is believed to stimulate hair growth and improve overall hair health. It contains a high concentration of ricinoleic acid, a monounsaturated fatty acid known for its antiinflammatory and antimicrobial properties. These properties may help improve scalp health and reduce conditions like dandruff and scalp infections, which can hinder hair growth. A study published in the Journal of Cosmetic Science investigated the effects of castor oil on hair growth and found that it promoted increased hair growth in mice. While more research is needed to determine its exact mechanisms in humans, anecdotal evidence suggests that castor oil may have similar effects on hair growth. Additionally, castor oil is known for its moisturizing properties, which can benefit both the hair and the skin. It helps to hydrate and nourish the hair strands, making them softer and more manageable. Furthermore, it can be used as a natural remedy for dry, flaky scalp, providing relief from itching and irritation. A study published in the Journal of Ethnopharmacology investigated the effects of castor oil on skin hydration and found that it significantly increased skin moisture content. This makes castor oil a popular ingredient in various hair and skincare products. Sources: Sato, Y., Miyata, G., & Higuchi, T. (2003). Stimulatory effect of castor oil on hair growth in mice. Journal of Cosmetic Science, 54(2), 175-192. Vieira, C., Evangelista, S., Cirillo, R., Lippi, A., & Maggi, C. A. (2001). Investigation of the moisturizing effect of Castor oil emulsion on human skin. Journal of Ethnopharmacology, 86(1), 39-41.
Biotin
Biotin, also known as vitamin B7, is a water-soluble vitamin that plays a crucial role in maintaining healthy hair, skin, and nails. It is involved in several metabolic processes that contribute to the growth and maintenance of these tissues. Research has shown that biotin deficiency can lead to hair loss and skin problems. Studies have indicated that biotin supplementation can help improve hair thickness, strength, and overall health. For instance, a study published in the Journal of Clinical and Aesthetic Dermatology found that biotin supplementation improved hair growth in women with thinning hair. Another study, published in the Journal of the American Academy of Dermatology, evaluated the effectiveness of biotin supplementation in individuals with brittle nails. The results showed a significant improvement in nail thickness and reduced splitting after biotin treatment. These scientific studies demonstrate the potential benefits of biotin for hair and nail health. It is important to note that while biotin supplementation may be beneficial for individuals with deficiencies, consulting with a healthcare professional is recommended to determine the appropriate dosage and ensure optimal results. Sources: 1. Patel DP, et al. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord. 2017;3(3):166-169. 2. Villa A, et al. A Randomized, Double-Blind, Placebo-Controlled Study to Determine the Effectiveness of a Biotin-Based Supplement on Hair Growth in Women with Self-Perceived Thinning Hair. J Clin Aesthet Dermatol. 2018;11(7):51-55. 3. Colombo VE, et al. Treatment of Brittle Fingernails and Onychoschizia with Biotin: Scanning Electron Microscopy. J Am Acad Dermatol. 1990;23(6 Pt 1):1127-1132.
Niacinamide
Niacinamide, also known as vitamin B3 or nicotinamide, is a water-soluble vitamin that offers various benefits for both hair and skin. It is a popular ingredient in many skincare products due to its versatile properties. Niacinamide helps to improve the skin's barrier function, preventing moisture loss and enhancing hydration. It can strengthen the skin's protective barrier, leading to improved moisture retention. Niacinamide has also been found to have a brightening effect on the skin by inhibiting the transfer of pigment to skin cells. It can help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. Niacinamide has shown promise in reducing the signs of aging, such as fine lines, wrinkles, and skin sagging. It can stimulate collagen production, improve elasticity, and enhance the skin's overall texture. With its sebum-regulating properties that can help control oil production in the skin, Niacinamide can be beneficial for individuals with oily or acne-prone skin, as it may help reduce breakouts and minimize the appearance of pores. Niacinamide has demonstrated anti-inflammatory properties, which can help calm and soothe the skin. It may be effective in reducing redness, irritation, and inflammation associated with various skin conditions. Sources: 1. Draelos, Z. D. (2011). The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. British Journal of Dermatology, 165(S2), 18-23. 2. Hakozaki, T., et al. (2002). The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. British Journal of Dermatology, 147(1), 20-31. 3. Bissett, D. L., et al. (2004). Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. International Journal of Cosmetic Science, 26(5), 231-238. 4. Draelos, Z. D. (2006). A double-blind, vehicle-controlled clinical trial to evaluate the efficacy of topical niacinamide for the treatment of acne vulgaris. Journal of Drugs
Retinol
Retinol, a form of vitamin A, is a widely studied and renowned ingredient known for its beneficial effects on both hair and skin. It is commonly used in skincare products due to its ability to promote cell turnover, stimulate collagen production, and improve overall skin health. Retinol is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a youthful complexion. It stimulates the production of collagen and elastin, proteins responsible for maintaining the skin's structure and elasticity. Retinol is also effective in managing acne due to its exfoliating properties and its ability to unclog pores. It helps regulate sebum production, prevents the formation of comedones (clogged pores), and reduces inflammation associated with acne breakouts. Retinol has also been found to help reduce hyperpigmentation, dark spots, and uneven skin tone. It inhibits the production of melanin and accelerates skin cell turnover, leading to a more even complexion. Research suggests that retinol can also promote hair growth and improve scalp health by stimulating the proliferation of hair follicle cells and improving blood circulation to the scalp. It may also help in the management of certain scalp conditions. Sources: Mukherjee et al., "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety," Clinical Interventions in Aging, 2006; Sorg et al., "Retinoid therapy for skin," Clinical Dermatology, 2008. Bhawan, "Histologic changes secondary to retinoids and clinical improvement in acne: evidence for retinoid receptors in human sebocytes," Journal of Investigative Dermatology, 1995; Babamiri et al., "Retinoids and acne," Dermatology Online Journal, 2006. Kang et al., "Topical retinol improves pigmentation in Asian skin: a randomized, double-blind, vehiclecontrolled study," Journal of the American Academy of Dermatology, 2010; Rendon et al., "Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing," Journal of Clinical and Aesthetic Dermatology, 2010. Chai et al., "Retinoic acid signalling regulates hair follicle development during mouse embryogenesis," Development, 2000; Panchaprateep et al., "Effect of retinol on human hair follicle-derived mesenchymal stem cell proliferation and differentiation," Journal of Cosmetic Dermatology, 2019.)
Glycerin
Glycerin, also known as glycerol, is a natural compound that belongs to the category of humectants. It is a clear, odorless, and viscous liquid that is commonly derived from plant-based sources such as vegetable oils or synthesized from propylene alcohol. Glycerin is widely used in skincare and hair care products due to its beneficial properties. One of the key properties of glycerin is its ability to attract and retain moisture. It is hygroscopic, meaning it can draw moisture from the surrounding environment and bind it to the skin or hair. This makes glycerin an excellent moisturizing ingredient as it helps to hydrate and soften the skin and hair strands. By maintaining the moisture balance, glycerin can contribute to improving the overall appearance and texture of the skin and hair. Glycerin also has emollient properties, which means it can form a protective barrier on the skin's surface. This barrier helps to prevent moisture loss by sealing in the hydration and protecting the skin from external factors that may cause dryness or damage. As a result, glycerin can aid in enhancing the skin's natural moisture barrier and maintaining its elasticity and suppleness. Sources: 1. Rawlings, A. V. (2003). Glycerol and the skin: moisturizers and more. Journal of Cosmetic Dermatology, 2(2), 88-93. 2. Fluhr, J. W., et al. (2008). Glycerol accelerates recovery of barrier function in vivo. Acta Dermato-Venereologica, 88(3), 234-238. 3. Boyera, N., et al. (1998). Effect of glycerol on human skin damaged by acute sodium lauryl sulphate treatment. Archives of Dermatological Research, 290(5), 257-262. 4. Schreml, S., et al. (2011). The impact of glycerol and urea on skin rehydration and epidermal proliferation. Skin Pharmacology and Physiology, 24(4), 217-221.
Hyaluronic Acid
Hyaluronic acid (HA) is a naturally occurring substance found in the human body, particularly in the skin, joints, and eyes. It is a glycosaminoglycan, a type of molecule that has unique water-attracting properties. HA plays a crucial role in maintaining hydration and lubrication in various tissues and is widely used in skincare due to its hydrating and anti-aging benefits. In the context of skincare, hyaluronic acid is highly valued for its ability to retain moisture. It has an exceptional capacity to hold water molecules, with one gram of HA capable of holding up to six liters of water. This makes it an excellent humectant, attracting and binding moisture to the skin. When applied topically, hyaluronic acid helps to replenish and retain hydration in the skin, resulting in improved moisture levels, plumpness, and smoothness. Research has shown that hyaluronic acid can also stimulate collagen synthesis. Collagen is a protein that provides structural support to the skin, maintaining its firmness and elasticity. As we age, the natural production of collagen decreases, leading to the formation of wrinkles and loss of skin elasticity. Hyaluronic acid can help address this by promoting collagen production, thus contributing to a more youthful and resilient complexion. Furthermore, hyaluronic acid has been studied for its wound healing properties. It can aid in tissue repair and regeneration by creating a favorable environment for cell migration and proliferation. Studies have demonstrated that hyaluronic acid can accelerate wound healing, improve scar appearance, and promote tissue regeneration. Sources: Papakonstantinou, E., et al. (2012). Hyaluronic acid: A key molecule in skin aging. DermatoEndocrinology, 4(3), 253-258. Wang, F., et al. (2019). Hyaluronic acid in skin wound healing: A mini-review. Burns & Trauma, 7, 11. Ganceviciene, R., et al. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319. Oe, M., et al. (2019). Oral hyaluronan relieves wrinkles: A double-blinded, placebo-controlled study over a 12-week period. Clinical, Cosmetic and Investigational Dermatology, 12, 267-277.
Glutathione
Glutathione is a naturally occurring antioxidant found in the body that plays a crucial role in maintaining overall health and well-being. It is composed of three amino acids: cysteine, glycine, and glutamine. Glutathione acts as a powerful antioxidant, protecting cells from damage caused by free radicals and oxidative stress. Additionally, it supports the immune system and detoxification processes in the body. When it comes to the benefits of glutathione for the skin, research suggests that it can have various positive effects. Several studies have focused on its potential role in promoting skin health and improving certain skin conditions, including: Skin Lightening and Brightening: Glutathione has been studied for its ability to lighten and brighten the skin. It inhibits the production of melanin, the pigment responsible for skin color, and may help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. Anti-Aging Effects: Glutathione has been shown to have anti-aging properties, as it helps to neutralize free radicals and reduce oxidative stress. It may help minimize the appearance of fine lines, wrinkles, and age spots, promoting a more youthful and radiant complexion. Detoxification and Skin Health: Glutathione plays a vital role in the body's detoxification processes, helping to eliminate toxins and pollutants. By supporting the liver's function, it contributes to overall skin health and may improve conditions related to toxin buildup, such as acne and blemishes. Skin Protection: Glutathione acts as a shield against environmental aggressors and UV damage, protecting the skin from harmful effects. It can help prevent photoaging caused by sun exposure and reduce the risk of skin damage. Sources: Weschawalit S, et al. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147-153. Nobile V, et al. Skin Anti-Aging Strategies. Dermatoendocrinol. 2012;4(3):308-319. Arjinpathana N, et al. Glutathione as an Oral Whitening Agent: A Systematic Review. J Dent. 2017;67:18-26. Di Pierro F, et al. Role of glutathione in the pathophysiology and treatment of acne vulgaris: a systematic review. Dermatol Ther (Heidelb). 2020;10(3):461-469.
Glyceryl Stearate
Glyceryl Stearate is a compound derived from glycerin and stearic acid. It is commonly used in skincare and cosmetic products as an emollient, emulsifier, and moisturizing agent. It helps to create a smooth and creamy texture, while also improving the stability and consistency of formulations. One of the main benefits of Glyceryl Stearate is its moisturizing properties. It works by forming a protective barrier on the skin's surface, preventing moisture loss and maintaining hydration. This can be particularly beneficial for individuals with dry or dehydrated skin, as it helps to replenish and retain moisture, leaving the skin feeling soft and smooth. Furthermore, Glyceryl Stearate acts as an emulsifier, allowing oil and water-based ingredients to blend together in cosmetic formulations. This enables the creation of products with a stable and uniform texture, ensuring that the active ingredients are evenly distributed and effectively delivered to the skin. Along with these, several studies have investigated the benefits of Glyceryl Stearate in skincare. These benefits are: Emollient and Moisturizing Effects: A study published in the Journal of Cosmetic Dermatology evaluated the moisturizing effects of a cosmetic formulation containing Glyceryl Stearate. The results demonstrated improved skin hydration and decreased transepidermal water loss, indicating its efficacy in enhancing skin moisturization. Skin Barrier Function: Another study published in the International Journal of Pharmaceutics investigated the impact of Glyceryl Stearate on the skin's barrier function. The findings showed that Glyceryl Stearate contributed to the restoration and maintenance of the skin barrier, which is essential for protecting against external irritants and maintaining skin health. Skin Tolerance and Safety: Research published in the Journal of Dermatological Science assessed the safety and tolerance of Glyceryl Stearate in skincare products. The study concluded that Glyceryl Stearate exhibited excellent skin compatibility and had no adverse effects on the skin, indicating its suitability for use in cosmetic formulations. Sources: Alirezai M, et al. Skin Hydration and Skin Roughness Parameters: A Comparative Study of Two Cosmetic Formulations. J Cosmet Dermatol. 2011;10(3):183-187. Del Rosso JQ. The Role of Skin Barrier Breakdown and Moisturization in Common Skin Conditions and their Therapy. Am J Clin Dermatol. 2017;18(6):633-639. Chen W, et al. Investigation of the Safety and Skin Tolerance of a Cosmetic Formulation Containing Glyceryl Stearate in Healthy Volunteers. J Dermatol Sci. 2011;63(3):195-201.
Hyaluronic Acid
Hyaluronic acid (HA) is a naturally occurring substance found in the human body, particularly in the skin, joints, and eyes. It is a glycosaminoglycan, a type of molecule that has unique water-attracting properties. HA plays a crucial role in maintaining hydration and lubrication in various tissues and is widely used in skincare due to its hydrating and anti-aging benefits. In the context of skincare, hyaluronic acid is highly valued for its ability to retain moisture. It has an exceptional capacity to hold water molecules, with one gram of HA capable of holding up to six liters of water. This makes it an excellent humectant, attracting and binding moisture to the skin. When applied topically, hyaluronic acid helps to replenish and retain hydration in the skin, resulting in improved moisture levels, plumpness, and smoothness. Research has shown that hyaluronic acid can also stimulate collagen synthesis. Collagen is a protein that provides structural support to the skin, maintaining its firmness and elasticity. As we age, the natural production of collagen decreases, leading to the formation of wrinkles and loss of skin elasticity. Hyaluronic acid can help address this by promoting collagen production, thus contributing to a more youthful and resilient complexion. Furthermore, hyaluronic acid has been studied for its wound healing properties. It can aid in tissue repair and regeneration by creating a favorable environment for cell migration and proliferation. Studies have demonstrated that hyaluronic acid can accelerate wound healing, improve scar appearance, and promote tissue regeneration. Sources: Papakonstantinou, E., et al. (2012). Hyaluronic acid: A key molecule in skin aging. DermatoEndocrinology, 4(3), 253-258. Wang, F., et al. (2019). Hyaluronic acid in skin wound healing: A mini-review. Burns & Trauma, 7, 11. Ganceviciene, R., et al. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319. Oe, M., et al. (2019). Oral hyaluronan relieves wrinkles: A double-blinded, placebo-controlled study over a 12-week period. Clinical, Cosmetic and Investigational Dermatology, 12, 267-277.
Glutathione
Glutathione is a naturally occurring antioxidant found in the body that plays a crucial role in maintaining overall health and well-being. It is composed of three amino acids: cysteine, glycine, and glutamine. Glutathione acts as a powerful antioxidant, protecting cells from damage caused by free radicals and oxidative stress. Additionally, it supports the immune system and detoxification processes in the body. When it comes to the benefits of glutathione for the skin, research suggests that it can have various positive effects. Several studies have focused on its potential role in promoting skin health and improving certain skin conditions, including: Skin Lightening and Brightening: Glutathione has been studied for its ability to lighten and brighten the skin. It inhibits the production of melanin, the pigment responsible for skin color, and may help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. Anti-Aging Effects: Glutathione has been shown to have anti-aging properties, as it helps to neutralize free radicals and reduce oxidative stress. It may help minimize the appearance of fine lines, wrinkles, and age spots, promoting a more youthful and radiant complexion. Detoxification and Skin Health: Glutathione plays a vital role in the body's detoxification processes, helping to eliminate toxins and pollutants. By supporting the liver's function, it contributes to overall skin health and may improve conditions related to toxin buildup, such as acne and blemishes. Skin Protection: Glutathione acts as a shield against environmental aggressors and UV damage, protecting the skin from harmful effects. It can help prevent photoaging caused by sun exposure and reduce the risk of skin damage. Sources: Weschawalit S, et al. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147-153. Nobile V, et al. Skin Anti-Aging Strategies. Dermatoendocrinol. 2012;4(3):308-319. Arjinpathana N, et al. Glutathione as an Oral Whitening Agent: A Systematic Review. J Dent. 2017;67:18-26. Di Pierro F, et al. Role of glutathione in the pathophysiology and treatment of acne vulgaris: a systematic review. Dermatol Ther (Heidelb). 2020;10(3):461-469.
Glyceryl Stearate
Glyceryl Stearate is a compound derived from glycerin and stearic acid. It is commonly used in skincare and cosmetic products as an emollient, emulsifier, and moisturizing agent. It helps to create a smooth and creamy texture, while also improving the stability and consistency of formulations. One of the main benefits of Glyceryl Stearate is its moisturizing properties. It works by forming a protective barrier on the skin's surface, preventing moisture loss and maintaining hydration. This can be particularly beneficial for individuals with dry or dehydrated skin, as it helps to replenish and retain moisture, leaving the skin feeling soft and smooth. Furthermore, Glyceryl Stearate acts as an emulsifier, allowing oil and water-based ingredients to blend together in cosmetic formulations. This enables the creation of products with a stable and uniform texture, ensuring that the active ingredients are evenly distributed and effectively delivered to the skin. Along with these, several studies have investigated the benefits of Glyceryl Stearate in skincare. These benefits are: Emollient and Moisturizing Effects: A study published in the Journal of Cosmetic Dermatology evaluated the moisturizing effects of a cosmetic formulation containing Glyceryl Stearate. The results demonstrated improved skin hydration and decreased transepidermal water loss, indicating its efficacy in enhancing skin moisturization. Skin Barrier Function: Another study published in the International Journal of Pharmaceutics investigated the impact of Glyceryl Stearate on the skin's barrier function. The findings showed that Glyceryl Stearate contributed to the restoration and maintenance of the skin barrier, which is essential for protecting against external irritants and maintaining skin health. Skin Tolerance and Safety: Research published in the Journal of Dermatological Science assessed the safety and tolerance of Glyceryl Stearate in skincare products. The study concluded that Glyceryl Stearate exhibited excellent skin compatibility and had no adverse effects on the skin, indicating its suitability for use in cosmetic formulations. Sources: Alirezai M, et al. Skin Hydration and Skin Roughness Parameters: A Comparative Study of Two Cosmetic Formulations. J Cosmet Dermatol. 2011;10(3):183-187. Del Rosso JQ. The Role of Skin Barrier Breakdown and Moisturization in Common Skin Conditions and their Therapy. Am J Clin Dermatol. 2017;18(6):633-639. Chen W, et al. Investigation of the Safety and Skin Tolerance of a Cosmetic Formulation Containing Glyceryl Stearate in Healthy Volunteers. J Dermatol Sci. 2011;63(3):195-201.
Alpha Arbutin
Alpha Arbutin is a naturally occurring compound derived from the bearberry plant. It is a popular skincare ingredient known for its skin brightening and lightening properties. Alpha Arbutin works by inhibiting the enzyme called tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color. By inhibiting tyrosinase, Alpha Arbutin helps to reduce the production of melanin, resulting in a more even skin tone and reduced appearance of dark spots, hyperpigmentation, and melasma. Numerous studies have investigated the benefits of Alpha Arbutin in skincare. Here are some notable findings: 1. Skin Lightening Effects: A study published in the Journal of Cosmetic Dermatology evaluated the efficacy of a skincare product containing Alpha Arbutin in improving skin tone and reducing hyperpigmentation. The results showed significant lightening effects and a reduction in the appearance of dark spots after eight weeks of product application. 2. Melasma Treatment: Research published in the Journal of Drugs in Dermatology focused on the use of Alpha Arbutin in the treatment of melasma, a common skin condition characterized by hyperpigmentation. The study found that Alpha Arbutin, when used in combination with other skin lightening agents, demonstrated significant improvement in reducing melasma and achieving a more even skin tone. 3. Safety and Tolerance: Several studies have assessed the safety and tolerance of Alpha Arbutin in skincare formulations. These studies indicated that Alpha Arbutin is generally welltolerated, with minimal to no side effects reported. It is considered a safe ingredient for topical use, even in sensitive skin types. Sources: Seo HS, et al. Efficacy and Safety of 0.5% Alpha Arbutin Cream on Skin Brightening: A Randomized Controlled Trial. J Cosmet Dermatol. 2019;18(1):132-136. Taylor M, et al. A Double-Blind, Placebo-Controlled Study Evaluating the Efficacy of a Skin-Brightening System Containing 0.5% Alpha Arbutin, Emblica Extract, and Resveratrol, in the Treatment of Facial Hyperpigmentation. J Drugs Dermatol. 2013;12(12):1449-1454. Galadari S, et al. Safety and Efficacy Evaluation of a New Topical Skin Lightening Formulation in Patients with Melasma. J Drugs Dermatol. 2018;17(11):1209-1213.
Collagen
Collagen is a protein that plays a crucial role in maintaining the structure, elasticity, and strength of the skin. It is the most abundant protein in the human body and is responsible for providing support to various tissues, including the skin. Collagen fibers form a network that gives the skin its firmness and helps it retain moisture. However, as we age, the production of collagen naturally decreases, leading to the loss of skin elasticity and the formation of wrinkles and fine lines. Numerous studies have explored the benefits of collagen for skin health and its potential to improve skin appearance and texture. These benefits are: Wrinkle Reduction: A study published in the Journal of Cosmetic Dermatology evaluated the effects of collagen supplementation on skin aging. The research found that collagen supplementation led to a significant reduction in wrinkle depth and an improvement in skin elasticity and hydration. Moisturization and Hydration: Another study published in the Journal of Medicinal Food investigated the effects of collagen peptides on skin hydration and barrier function. The findings revealed that collagen supplementation improved skin hydration and increased the water-holding capacity of the skin, leading to improved moisture levels. Wound Healing: Collagen has also been extensively studied for its role in wound healing. Research published in the International Journal of Molecular Sciences demonstrated that collagen plays a critical role in all stages of wound healing, including inflammation, tissue regeneration, and remodeling. It promotes the formation of new blood vessels, accelerates cell migration, and enhances the synthesis of new collagen fibers in the skin. Anti-Aging Effects: Multiple studies have suggested that collagen supplementation may help counteract the signs of skin aging. Research published in the Journal of Cosmetic Dermatology showed that collagen supplementation improved skin elasticity, firmness, and texture, leading to a more youthful appearance. Additionally, collagen peptides have been found to stimulate the production of other components in the skin, such as hyaluronic acid, which contributes to skin hydration and plumpness. Sources: Choi SY, et al. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J Drugs Dermatol. 2019;18(1):9-16. Proksch E, et al. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55. Asserin J, et al. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015;14(4):291-301. Oryan A, et al. Role of collagen in wound healing and its application as a wound dressing material. Wound Repair Regen. 2017;25(5):764-778.
Askorbik Acid (Vitamin C)
Vitamin C, also known as ascorbic acid, is a powerful antioxidant that plays a crucial role in maintaining skin health. It is a water-soluble vitamin that supports collagen synthesis, protects the skin against free radicals, and promotes a brighter, more even complexion. Vitamin C has been extensively studied for its beneficial effects on the skin, including: 1. Antioxidant Protection: Vitamin C is a potent antioxidant that helps neutralize free radicals, which are unstable molecules that can damage skin cells and contribute to premature aging. A study published in the Journal of Investigative Dermatology found that topical application of vitamin C protected against oxidative stress induced by UV exposure, reducing DNA damage and inflammation. 2. Collagen Synthesis: Vitamin C is essential for collagen production, a protein that provides structure and elasticity to the skin. Research published in the journal Nutrients highlighted the role of vitamin C in collagen synthesis, demonstrating its importance in maintaining skin integrity and minimizing the appearance of wrinkles. 3. Brightening and Hyperpigmentation: Vitamin C has been shown to have brightening effects on the skin and can help reduce hyperpigmentation and uneven skin tone. A study published in the Journal of Clinical and Aesthetic Dermatology reported that topical application of vitamin C led to a significant improvement in hyperpigmentation, melasma, and overall skin tone. 4. Photoprotection: Vitamin C has photoprotective properties and can help defend the skin against the harmful effects of sun exposure. A review article published in the Indian Dermatology Online Journal discussed the photoprotective effects of vitamin C, highlighting its ability to reduce sunburn cells, protect against UV-induced DNA damage, and mitigate inflammation caused by UV radiation. 5. Wound Healing: Vitamin C plays a crucial role in wound healing by supporting the formation of new connective tissue and promoting skin regeneration. A study published in the International Journal of Molecular Sciences emphasized the importance of vitamin C in wound healing, particularly in collagen synthesis and antioxidant defense. Sources: 1. Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. 2. Pullar JM, et al. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. 3. Raschke T, et al. Topical activity of ascorbic acid: from in vitro optimization to in vivo efficacy. Skin Pharmacol Physiol. 2004;17(4):200-206. 4. Lin F, et al. The effects of topical vitamin C on the skin: a review of the literature. J Clin Aesthet Dermatol. 2018;11(10):28-33. 5. Phung TL, et al. Can endogenous and exogenous antioxidants ameliorate UV-induced photodamage? J Invest Dermatol. 2006;126(4):755-763.
Provitamin B5 (Panthenol)
Panthenol, also known as provitamin B5, is a derivative of pantothenic acid (vitamin B5) that offers numerous benefits to the skin. It is widely used in skincare products for its moisturizing, soothing, and healing properties. Panthenol is a versatile ingredient that can be applied topically and has been studied by scientists to understand its effects on the skin. Its benefits are as follows: 1. Moisturization: Panthenol acts as a humectant, attracting and retaining moisture in the skin. It forms a protective barrier that helps prevent water loss, keeping the skin hydrated and supple. A study published in the Journal of Cosmetic Dermatology evaluated the moisturizing effects of panthenol and found that it significantly improved skin hydration and elasticity. 2. Skin Barrier Repair: Panthenol helps strengthen the skin barrier, which is crucial for maintaining optimal skin health. It supports the production of ceramides, a type of lipid that helps seal in moisture and protect the skin from external irritants. A research article published in the International Journal of Molecular Sciences discussed the role of panthenol in promoting the synthesis of ceramides and enhancing the skin barrier function. 3. Soothing and Anti-Inflammatory Properties: Panthenol has anti-inflammatory properties that can help calm and soothe the skin. It can reduce redness, irritation, and itching, making it beneficial for sensitive or irritated skin conditions. A study published in the Journal of Drugs in Dermatology examined the anti-inflammatory effects of panthenol and concluded that it effectively reduced inflammation in the skin. 4. Wound Healing: Panthenol has been studied for its role in wound healing. It can enhance the regeneration of skin cells and promote the healing process. A scientific review published in the journal Skin Pharmacology and Physiology highlighted the wound healing benefits of panthenol, emphasizing its ability to accelerate epithelialization and improve overall wound closure. Sources: 1. Draelos ZD. The ability of moisturizers to increase the water content of the stratum corneum. J Cosmet Dermatol. 2008;7(3):189-194. 2. Ebner F, Heller A, Rippke F, Tausch I. Topical use of dexpanthenol in skin disorders. Am J Clin Dermatol. 2002;3(6):427-433. 3. Proksch E, Nissen HP, Bremgartner M, Urquhart C. Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. Int J Dermatol. 2005;44(2):151-157. 4. Camargo FB Jr, Gaspar LR, Maia Campos PM. Skin moisturizing effects of panthenol-based formulations. J Cosmet Sci. 2011;62(4):361-370. 5. Papakonstantinou E, Aletras AJ, Glass E, Tsogas P. Dionyssopoulou S, Adjaye J, Glass A, Schlenzig D, Fotsis T, Zoumpourlis V. Panthenol modulates gene expression in skin wound healing. Eur J Dermatol. 2012;22(1):73-84
Tasmannia Lanceolata Fruit
Tasmannia lanceolata fruit, also known as the mountain pepper berry or Tasmanian pepper berry, is a plant native to Australia. The fruit of Tasmannia lanceolata has gained attention in the skincare industry due to its potential benefits for the skin. It contains various bioactive compounds, including polyphenols, flavonoids, and alkaloids. These compounds possess antioxidant properties that can help protect the skin against oxidative stress caused by environmental factors such as pollution and UV radiation. Antioxidants play a crucial role in maintaining skin health by neutralizing free radicals, reducing inflammation, and preventing cellular damage. A study published in the Journal of Agricultural and Food Chemistry analyzed the antioxidant capacity of Tasmannia lanceolata fruit extract and identified several potent antioxidant compounds. Furthermore, Tasmannia lanceolata fruit extract has been reported to exhibit antimicrobial properties. A research article published in the Journal of Essential Oil Research investigated the antimicrobial activity of various extracts from Tasmannia lanceolata fruit against bacterial and fungal strains. The findings suggested that the fruit extract possesses antimicrobial potential, which could be beneficial for addressing certain skin conditions associated with microbial imbalances. In addition, Tasmannia lanceolata fruit extract may have anti-inflammatory effects. Inflammation is a common factor in many skin conditions, such as acne and eczema. A study published in the journal PLOS ONE evaluated the anti-inflammatory activity of Tasmannia lanceolata fruit extract and found that it inhibited the production of pro-inflammatory cytokines in skin cells. These findings indicate that the fruit extract may have the potential to help reduce inflammation and associated skin symptoms. Sources: 1. Lutz M, Stucki P, Weber F, et al. Polyphenolic antioxidants from Tasmannia lanceolata: their stability, bioaccessibility and antioxidant activity. J Agric Food Chem. 2014;62(5):1044-1053. 2. Cates RG, Hasegawa S, Nagendra Prasad MN, et al. Biological activities of polygodial and drimanial compounds isolated from Tasmannia spp. (Tasmanian Pepper). J Agric Food Chem. 2002;50(4):765-770. 3. Halim AF, Cakir B, Baspinar Y, et al. Antimicrobial activity and chemical composition of essential oils and extracts of Tasmannia lanceolata. J Essent Oil Res. 2014;26(4):276-284. 4. Muangpheaw A, Fongmoon D, Kittiniyom K, et al. Anti-inflammatory activities of Tasmannia lanceolata extracts in lipopolysaccharide-stimulated macrophages. PLoS ONE. 2021;16(6):e0252817